CBL Chemical Biology Lab

Nadège Lubin-Germain

Full Professor

Education & Career :

1992 : PhD University of Paris-Sud  (Advisor: Prof. André Lubineau)
1993 : Post-doc, Jülich, Germany
1994 : Temporary Assistant Professor, Cergy-Pontoise University
1994-2010 : Associate Professor, Cergy-Pontoise University
2001 :  CNRS Delegation
2004 : Habilitation à Diriger des Recherches (HDR)
2010 : Full Professor, Cergy-Pontoise University

Research Interests :

Glycochemistry: Synthesis of C-glycosides.

Nucleoside Chemistry : Synthesis of C-nucleosides with antiviral and antitumoral activity.

Green Chemistry.

 

Recent Publications :

Copper(II) SBA-‚Äč15: A reusable catalyst for azide-‚Äčalkyne cycloaddition. Jlalia, I.; Gallier, F.; Brodie-Linder, N.; Uziel, J.; Auge, J.; Lubin-Germain, N. J. Mol. Catal. A: Chem. 2014, 393, 56-61.

Straightforward glycosylation of alcohols and amino acids mediated by ionic liquid. Monasson, O.; Sizun-Thomé, G.; Lubin-Germain N.; Uziel, J.; Augé, J. Carbohydr. Res. 2012, 352, 202-205.

Indium mediated alkynylation of sugars. Synthesis of C-glycosyl compounds bearing a protected amino alcohol moiety. Ayed, C.; Palmier, S.; Lubin-Germain, N.; Uziel, J.; Augé, J. Carbohydr. Res. 2010, 345, 2566-2570.

Huisgen cycloaddition reaction of C-alkynyl ribosides under micellar catalysis: synthesis of ribavirin analogues. Ait Youcef, R.; Dos Santos, M.; Roussel, S. ; Baltaze, J.P. ; Lubin-Germain, N. ; Uziel, J. J. Org. Chem. 2009, 74, 4318-4323.

Direct C-glycosylation by indium-mediated alkynylation on sugar anomeric position. Lubin-Germain, N. ; Baltaze, J. P. ; Coste, A. ; Hallonet, A. ; Lauréano H. ; Legrave, G. ; Uziel, J. ; Augé, J. Org. Lett. 2008, 10, 725-728.

Gram-scale preparation of a p-(C-glucopyranosyl)-l-phenylalanine derivative by a Negishi cross-coupling reaction. Ousmer, M.; Boucard, V.; Lubin-Germain, N.; Uziel, J.; Augé, J. Eur. J. Org. Chem.2006, 1216-1221.

 

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